Thierry Calandra Selected Research

Macrophage Migration-Inhibitory Factors

1/2021	Macrophage migration inhibitory factor promotes the migration of dendritic cells through CD74 and the activation of the Src/PI3K/myosin II pathway.
3/2016	Functional polymorphisms of macrophage migration inhibitory factor as predictors of morbidity and mortality of pneumococcal meningitis.
2/2013	Release of macrophage migration inhibitory factor by neuroendocrine-differentiated LNCaP cells sustains the proliferation and survival of prostate cancer cells.
1/2013	Macrophage migration inhibitory factor deficiency is associated with impaired killing of gram-negative bacteria by macrophages and increased susceptibility to Klebsiella pneumoniae sepsis.
11/2012	Increased macrophage migration inhibitory factor (MIF) plasma levels in acute HIV-1 infection.
2/2012	A functional microsatellite of the macrophage migration inhibitory factor gene associated with meningococcal disease.
2/2010	Expression and function of macrophage migration inhibitory factor (MIF) in melioidosis.
11/2009	Histone deacetylase inhibitors repress macrophage migration inhibitory factor (MIF) expression by targeting MIF gene transcription through a local chromatin deacetylation.
10/2009	A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor.
12/2007	Regulation of constitutive and microbial pathogen-induced human macrophage migration inhibitory factor (MIF) gene expression.

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Thierry Calandra Research Topics

Disease

30	Sepsis (Septicemia) 01/2021 - 01/2003
28	Infections 05/2022 - 01/2005
17	Septic Shock (Toxic Shock Syndrome) 01/2021 - 01/2002
14	Neoplasms (Cancer) 05/2022 - 03/2002
9	Communicable Diseases (Infectious Diseases) 01/2019 - 03/2004
8	Invasive Fungal Infections 09/2017 - 08/2005
8	Candidiasis (Moniliasis) 01/2014 - 10/2004
7	Leukemia 05/2022 - 03/2008
7	Shock 01/2021 - 01/2006
7	Critical Illness (Critically Ill) 09/2017 - 08/2005
7	Inflammation (Inflammations) 01/2017 - 01/2003
7	Invasive Candidiasis 01/2014 - 02/2005
7	Mycoses (Diseases, Fungus) 01/2014 - 10/2004
6	Fever (Fevers) 03/2013 - 01/2005
5	Candidemia 01/2020 - 11/2005
4	HIV Infections (HIV Infection) 04/2022 - 01/2011
4	Febrile Neutropenia 01/2022 - 01/2005
4	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 04/2002
4	Aspergillosis 01/2017 - 08/2005
4	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2008 - 03/2004
4	Coronary Artery Disease (Coronary Atherosclerosis) 01/2008 - 03/2004
3	Lung Diseases (Lung Disease) 01/2021 - 08/2005
3	Pneumonia (Pneumonitis) 01/2019 - 07/2005
3	Neutropenia 01/2018 - 08/2005
3	Neonatal Sepsis 01/2017 - 07/2011
3	Acquired Immunodeficiency Syndrome (AIDS) 01/2015 - 06/2009
3	Ulcer 01/2008 - 03/2004
3	Venous Thrombosis (Deep-Vein Thrombosis) 01/2008 - 03/2004
3	Hemorrhage 01/2008 - 03/2004
3	Acute Lung Injury 01/2008 - 03/2004
3	Rheumatoid Arthritis 10/2006 - 10/2005
2	COVID-19 10/2022 - 01/2021
2	Bacterial Meningitis 01/2019 - 03/2016
2	Endotoxemia 01/2017 - 05/2007
2	Meningococcal Infections 02/2012 - 05/2007
2	Carcinogenesis 11/2009 - 12/2007
2	Peritonitis 03/2008 - 11/2005
2	Adrenal Insufficiency (Adrenal Gland Hypofunction) 01/2008 - 01/2008
2	Hypotension (Low Blood Pressure) 01/2008 - 01/2008

Drug/Important Bio-Agent (IBA)

22	Macrophage Migration-Inhibitory FactorsIBA 01/2021 - 04/2002
16	CytokinesIBA 01/2021 - 01/2002
13	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 03/2004
8	Pharmaceutical PreparationsIBA 01/2021 - 11/2004
8	AntibodiesIBA 03/2016 - 01/2003
6	Fluconazole (Zonal)FDA LinkGeneric 01/2018 - 08/2005
6	Voriconazole (Vfend)FDA LinkGeneric 01/2017 - 11/2005
5	Biomarkers (Surrogate Marker)IBA 10/2022 - 07/2012
5	SteroidsIBA 01/2017 - 03/2004
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2014 - 01/2006
5	Protein CIBA 03/2008 - 03/2004
4	VaccinesIBA 01/2015 - 06/2009
4	Antifungal AgentsIBA 01/2014 - 11/2005
4	Proteins (Proteins, Gene)FDA Link 07/2012 - 01/2007
4	Amphotericin B (Amphotericin)FDA LinkGeneric 01/2009 - 08/2005
3	ProcalcitoninIBA 01/2021 - 04/2011
3	GlucocorticoidsIBA 01/2017 - 05/2007
3	EchinocandinsIBA 01/2017 - 08/2005
3	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2014 - 10/2006
3	Hormones (Hormone)IBA 02/2013 - 05/2007
3	MannansIBA 01/2010 - 02/2005
3	Caspofungin (Cancidas)FDA Link 05/2009 - 11/2005
3	Neuromuscular Blocking AgentsIBA 01/2008 - 03/2004
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2008 - 03/2004
3	Blood Glucose (Blood Sugar)IBA 01/2008 - 03/2004
3	AzolesIBA 01/2008 - 08/2005
3	Hemoglobins (Hemoglobin)IBA 01/2008 - 03/2004
3	Crystalloid SolutionsIBA 01/2008 - 03/2004
3	Dopamine (Intropin)FDA LinkGeneric 01/2008 - 03/2004
3	Dobutamine FDA LinkGeneric 01/2008 - 03/2004
3	Colloids (Colloid)IBA 01/2008 - 03/2004
2	Biological ProductsIBA 01/2021 - 01/2003
2	Anti-Infective Agents (Microbicides)IBA 01/2021 - 03/2002
2	Interleukin-6 (Interleukin 6)IBA 01/2017 - 07/2012
2	Interleukin-8 (Interleukin 8)IBA 01/2017 - 07/2012
2	DNA (Deoxyribonucleic Acid)IBA 01/2014 - 06/2009
2	AntigensIBA 01/2012 - 01/2010
2	EndotoxinsIBA 07/2011 - 01/2003
2	Imipenem FDA Link 10/2009 - 09/2009
2	LipidsIBA 01/2009 - 10/2007
2	Proton Pump InhibitorsIBA 01/2008 - 01/2008
1	midostaurinIBA 01/2022
1	gilteritinibIBA 01/2022
1	venetoclaxIBA 01/2022
1	quizartinibIBA 01/2022
1	Inotuzumab OzogamicinIBA 01/2022

Therapy/Procedure

32	Therapeutics 04/2022 - 10/2003
9	Critical Care (Surgical Intensive Care) 09/2017 - 03/2004
4	Drug Therapy (Chemotherapy) 11/2018 - 01/2005
4	Catheters 01/2017 - 07/2005
4	Resuscitation 05/2015 - 03/2004
3	Transplantation 05/2022 - 02/2004
3	Hemofiltration 01/2008 - 03/2004
3	Renal Dialysis (Hemodialysis) 01/2008 - 03/2004
3	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 01/2008 - 03/2004
3	Analgesia 01/2008 - 03/2004
3	Length of Stay 01/2008 - 10/2004
2	Biological Therapy 05/2022 - 01/2022
2	Central Venous Catheters 01/2020 - 11/2005
2	Glycemic Control 01/2008 - 01/2008
2	Artificial Respiration (Mechanical Ventilation) 01/2008 - 01/2008